Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.61 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.61 |
| ▸ | GAPDH | P04406 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258842 | 1.00 | ADORA3 (0.69) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL472571 | 0.83 | HSPA8 (0.72) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL472569 | 0.83 | HSPA8 (0.72) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7253894 | 0.81 | ADORA3 (1.00) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7257422 | 0.81 | ADORA3 (0.73) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7257417 | 0.81 | ADORA3 (0.73) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7253814 | 0.81 | ADORA3 (0.81) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7253816 | 0.81 | ADORA3 (0.81) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL27758010 | 0.80 | HSPA5 (0.73) | ADORA3HSPA5HSPA8GAPDHHSD17B10 | |
| SCHEMBL7253856 | 0.80 | ADORA3 (0.77) | ADORA3HSPA5HSPA8GAPDHHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |