Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400759 | 0.88 | CTSS (0.52) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL3205842 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL629960 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL627379 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL2159319 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL905289 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL16710011 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL12189206 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL3825684 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB | |
| SCHEMBL1951088 | 0.81 | CTSS (0.67) | CTSSCTSKL3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101449-A2 | PROCESS FOR THE PREPARATION OF 3,3,4,4-TETRAFLUOROPYRROLIDINE AND DERIVATIVES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-12-11 | — | — | WO | disclosed |