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SCHEMBL3205842

SCHEMBL3205842

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nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 3/20 0.67
▸ CTSK P43235 3/20 0.67
▸ ALDH1A1 P00352 1/20 0.54
▸ KMT2A Q03164 1/20 0.48
▸ PSENEN Q9NZ42 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CA2 P00918 3/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA7 P43166 1/20 0.47
▸ POLB P06746 1/20 0.44
▸ TYR P14679 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1951088 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL3825684 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL627379 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL2159319 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL905289 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL16710011 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL12189206 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
SCHEMBL629960 1.00 CTSS (0.67) CTSSCTSKALDH1A1KMT2APSENEN
Water SCHEMBL5203435 0.98 CTSK (0.69) CTSSCTSKALDH1A1KMT2APSENEN
Water SCHEMBL10884567 0.98 CTSK (0.69) CTSSCTSKALDH1A1KMT2APSENEN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 — — CN claimed
EP-4702033-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2026-03-04 — — EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
WO-2025215536-A1 MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER NOVARTIS AG (CH) 2025-10-16 — — WO disclosed
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 ZHOU YUHANG (US) 2025-09-11 — — US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 — — US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 — — EP disclosed
WO-2024224086-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2024-10-31 — — WO disclosed
EP-1781649-B1 SUBSTITUTED HYDANTOINS HOFFMANN LA ROCHE (CH) 2008-08-13 — — EP disclosed
CN-101175737-A Pro-drugs of N-thiazol-2yl-benzamide derivatives LUNDBECK & CO AS H (DK) 2008-05-07 — — CN disclosed
CN-100371323-C Cyanopyrrolidine derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 2008-02-27 — — CN disclosed
CN-1298703-C Cyanopyrrolidine Derivatives TAISHO PHARMACENTICAL CO LTD (JP) 2007-02-07 — — CN disclosed
US-20060264415-A1 Inhibitors of histone deacetylase METHYLGENE INC. 2006-11-23 — — US disclosed
US-20060264485-A1 Pro-drugs of N-thiazol-2-yl-benzamide derivatives H. LUNDBECK A/S (DK) 2006-11-23 — — US disclosed
CN-1772733-A Cyanopyrrolidine derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 2006-05-17 — — CN disclosed
US-20060041146-A1 Substituted hydantoins HOFFMANN-LA ROCHE AG 2006-02-23 — — US disclosed
CN-1715269-A Cyanopyrrolidine derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 2006-01-04 — — CN disclosed
CN-1474809-A Cyanopyrrolidine Derivatives ������ҩ��ʽ���� 2004-02-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060041146-A1 Substituted hydantoins HNMT, MAPK6, KYNU CTSS 1158/4885CTSK 1629/4885ALDH1A1 552/4885
US-20060264415-A1 Inhibitors of histone deacetylase HDAC1, HDAC3, HDAC11 CTSS 2338/4885CTSK 2409/4885ALDH1A1 781/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH CTSS 4120/4885CTSK 4487/4885ALDH1A1 3890/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CTSS 4022/4885CTSK 4661/4885ALDH1A1 2330/4885
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 PF4, F12, F2 CTSS 3675/4885CTSK 3949/4885ALDH1A1 4728/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 CTSS 4503/4885CTSK 4676/4885ALDH1A1 4748/4885
US-20060264485-A1 Pro-drugs of N-thiazol-2-yl-benzamide derivatives ADORA2A, ADORA2B, ADORA1 CTSS 2402/4885CTSK 2500/4885ALDH1A1 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.