SCHEMBL7258941

SCHEMBL7258941

CCC12CC3CC(CC(C3)C1(C)C)C2

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.34
GRIN2D O15399 4/20 0.32
GRIN3B O60391 4/20 0.32
GRIN1 Q05586 4/20 0.32
GRIN2A Q12879 4/20 0.32
GRIN2B Q13224 4/20 0.32
GRIN2C Q14957 4/20 0.32
GRIN3A Q8TCU5 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11702345 0.83 HSD11B1 (0.37) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28879425 0.80 HSD11B1 (0.33) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11676268 0.79 EPHX2 (0.34) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
Ammonia Solution, Strong SCHEMBL28147127 0.78 EPHX2 (0.33) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1940081 0.77 GRIN2D (0.32) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11681442 0.77 EPHX2 (0.39) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL28475919 0.74 SMN1; SMN2 (0.31) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL10774984 0.74 GRIN2D (0.31) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4140923 0.74 ALDH1A1 (0.38) HSD11B1
Hydrochloric Acid SCHEMBL4140930 0.72 HSD11B1 (0.42) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4008251-A TRACTION FLUID ADDITIVES SUN OIL COMPANY, (SUN RESEARCH AND DEVELOPMENT CO.) 1977-02-15 US claimed
EP-1346730-A1 Pretargeting methods and novel pretargeting conjugates NEORX CORPORATION (US) 2003-09-24 EP disclosed
US-6217869-B1 ADMINISTERING ANTIBODY, ANTIGEN, LIGAND COMPLEX NEORX CORPORATION 2001-04-17 US disclosed
US-6015897-A FOR CONJUGATION TO LIGAND/ANTILIGAND PAIR AND USE IN DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENT TO TARGETED SITE NEORX CORPORATION (US) 2000-01-18 US disclosed
EP-0733066-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-04-21 EP disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
EP-0158996-B1 PERFLUORO CARBON COMPOUND AQUEOUS DISPERSIONS AFFINITY BIOTECH, INC. (US) 1991-12-04 EP disclosed
US-4917930-A Perfluoro compound dispersions containing reduced amounts of surfactant and process of preparation ADAMANTECH, INC. (US) 1990-04-17 US disclosed
US-4889525-A WITH AQUEOUS DISPERSION OF OXYGEN CARRYING PERFLUORO COMPOUND AND DISPERSANT ADAMANTECH, INC. (US) 1989-12-26 US disclosed
WO-1984000686-A1 PERFLUOROCARBON EMULSIONS AND THEIR PREPARATION AND USE IN THERAPY SUN TECH INC (US) 1984-03-01 WO disclosed
US-4366169-A Use of perfluorocarbons as wound treatment SUN TECH, INC. (US) 1982-12-28 US disclosed
EP-0031353-A4 USE OF PERFLUOROCARBON AS BURN TREATMENT. SUNTECH (US) 1982-07-06 EP disclosed
EP-0031353-A1 USE OF PERFLUOROCARBON AS BURN TREATMENT. SUNTECH (US) 1981-07-08 EP disclosed
WO-1981000002-A1 USE OF PERFLUOROCARBON AS BURN TREATMENT SUNTECH (US) 1981-01-08 WO disclosed
US-4105798-A Perfluoro polycyclic compounds for use as synthetic blood and perfusion media SUN VENTURES, INC. (US) 1978-08-08 US disclosed
US-4043927-A Friction or tractive drive containing ethers of adamantanes SUN VENTURES, INC. (US) 1977-08-23 US disclosed
US-4041086-A HYDRAULIC FLUIDS, DIELECTRIC COOLANTS, TRACTION FLUIDS, LUBRICANTS ON SUN VENTURES, INC. (US) 1977-08-09 US disclosed
US-4008251-A TRACTION FLUID ADDITIVES SUN OIL COMPANY, (SUN RESEARCH AND DEVELOPMENT CO.) 1977-02-15 US disclosed
US-4008251-A TRACTION FLUID ADDITIVES SUN OIL COMPANY, (SUN RESEARCH AND DEVELOPMENT CO.) 1977-02-15 US disclosed