Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258912 | 0.86 | BAZ2A (0.46) | HPGDSCNR2CNR1BAZ2ANISCH | |
| SCHEMBL2775310 | 0.85 | CNR2 (0.58) | CNR2CNR1CA1CA2PTGS1 | |
| SCHEMBL7257521 | 0.84 | CNR2 (0.48) | CNR2CNR1CA1CA2PTGS1 | |
| SCHEMBL13422220 | 0.83 | HPGDS (0.52) | HPGDSCNR2CNR1BAZ2AAOC3 | |
| SCHEMBL13422226 | 0.83 | HPGDS (0.52) | HPGDSBAZ2AAOC3 | |
| SCHEMBL7254727 | 0.81 | CNR2 (0.48) | CNR2CNR1BAZ2ANISCHCA1 | |
| SCHEMBL7255183 | 0.81 | CNR2 (0.47) | CNR2CNR1BAZ2ANISCHCA1 | |
| SCHEMBL3588162 | 0.80 | PTGS1 (0.41) | CNR2CNR1NISCHCA1CA2 | |
| SCHEMBL7254028 | 0.80 | CNR2 (0.46) | CNR2CNR1NISCHCA1CA2 | |
| SCHEMBL13807622 | 0.78 | NISCH (0.39) | CNR2NISCHCA1CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062232-A1 | DERIVATIVES OF THIAZOLES USED FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-07-31 | — | — | WO | claimed |
| WO-2003062232-A1 | DERIVATIVES OF THIAZOLES USED FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-07-31 | — | — | WO | disclosed |