Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576966 | 0.84 | NPC1 (0.48) | KDM4EPOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22577342 | 0.78 | KDM4E (0.38) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22583929 | 0.78 | KDM4E (0.38) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22583938 | 0.78 | KDM4E (0.36) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22583878 | 0.78 | KDM4E (0.36) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL3477652 | 0.76 | KDM4E (0.44) | KDM4EPOLBLMNAAPEX1ALDH1A1 | |
| SCHEMBL22577174 | 0.76 | HTR7 (0.36) | KDM4EPOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22583821 | 0.76 | KDM4E (0.35) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22583791 | 0.76 | KDM4E (0.35) | KDM4EPOLBLMNAALDH1A1CYP1A2 | |
| SCHEMBL22577069 | 0.76 | KDM4E (0.41) | KDM4EPOLBLMNAAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029231-A1 | NEMATICIDAL TRIFLUOROBUTENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-04-10 | — | — | WO | disclosed |