Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15165357 | 0.89 | KDM4E (0.35) | KDM4EPOLBLMNAAPEX1ALOX5 | |
| SCHEMBL7017995 | 0.78 | — | — | |
| SCHEMBL22577026 | 0.78 | KDM4E (0.42) | KDM4EPOLBLMNAALDH1A1APEX1 | |
| SCHEMBL7259098 | 0.76 | HCAR2 (0.41) | KDM4EPOLBLMNAALDH1A1APEX1 | |
| SCHEMBL22577230 | 0.76 | KDM4E (0.41) | KDM4EPOLBLMNAALDH1A1APEX1 | |
| SCHEMBL22577069 | 0.76 | KDM4E (0.41) | KDM4EPOLBLMNAALDH1A1APEX1 | |
| SCHEMBL18827810 | 0.76 | HTR7 (0.32) | HTR7 | |
| SCHEMBL22584038 | 0.74 | KDM4E (0.39) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22577325 | 0.74 | KDM4E (0.39) | KDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL22577279 | 0.74 | KDM4E (0.39) | KDM4EPOLBLMNAALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634397-B2 | Process and intermediates for the preparation of Fluensulfone | ADAMA MAKHTESHIM LTD. (IL) | 2023-04-25 | — | — | US | disclosed |
| US-11352335-B2 | Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)THIO]-thiazole | ADAMA MAKHTESHIM, LTD. (IL) | 2022-06-07 | — | — | US | disclosed |
| US-11352335-B2 | Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)THIO]-thiazole | ADAMA MAKHTESHIM, LTD. (IL) | 2022-06-07 | — | — | US | disclosed |
| US-11352335-B2 | Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)THIO]-thiazole | ADAMA MAKHTESHIM, LTD. (IL) | 2022-06-07 | — | — | US | disclosed |
| US-20220002258-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE | ADAMA MAKHTESHIM LTD. (IL) | 2022-01-06 | — | — | US | disclosed |
| US-20210387955-A1 | SYNTHESIS OF 1,1,2-TRIFLUORO-4-(SUBSTITUTED SUFONYL)-BUT-1-ENE | ADAMA MAKHTESHIM LTD. (IL) | 2021-12-16 | — | — | US | disclosed |
| CN-112996777-A | Synthesis of 1,1, 2-trifluoro-4- (substituted sulfonyl) -but-1-enes | 阿达玛马克西姆有限公司 | 2021-06-18 | — | — | CN | disclosed |
| US-11026425-B2 | Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | ADAMA MAKHTESHIM LTD. (IL) | 2021-06-08 | — | — | US | disclosed |
| CN-112930342-A | Process and intermediates for preparing difluoride sulfones | 阿达玛马克西姆有限公司 | 2021-06-08 | — | — | CN | disclosed |
| US-20210070719-A1 | SYNTHESIS OF 5-CHLORO-2-[(3,4,4-TRIFLUORO-3-BUTEN-1-YL)THIO]-THIAZOLE | ADAMA MAKHTESHIM, LTD. (IL) | 2021-03-11 | — | — | US | disclosed |
| US-20070155706-A1 | Active substance combinations that have nemticidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | ADAMA MAKHTESHIM LTD. (IL) | 2007-07-05 | — | — | US | disclosed |
| US-20070155706-A1 | Active substance combinations that have nemticidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | ADAMA MAKHTESHIM LTD. (IL) | 2007-07-05 | — | — | US | disclosed |
| US-20060004196-A1 | Method for producing heterocyclic fluoroalkenyl sulfones | MAKHTESHIM CHEMICAL WORKS, LTD. (IL) | 2006-01-05 | — | — | US | disclosed |
| EP-1519928-A1 | METHOD FOR PRODUCING HETEROCYCLIC FLUOROALKENYL SULFONES | Bayer CropScience AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| US-6734198-B1 | SUCH AS 5-CHLORO-2-(3,4,4- TRIFLUORO-3-BUTENYLTHIO)THIAZOLE | NIHON BAYER AGROCHEM K.K. (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-1200418-B1 | NEMATICIDAL TRIFLUOROBUTENES | BAYER CROPSCIENCE KK (JP) | 2004-03-31 | — | — | EP | disclosed |
| WO-2004005268-A1 | METHOD FOR PRODUCING HETEROCYCLIC FLUOROALKENYL SULFONES | BAYER CROPSCIENCE AG (DE) | 2004-01-15 | — | — | WO | disclosed |
| EP-1200418-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-05-02 | — | — | EP | disclosed |
| JP-2001019685-A | NEMATOCIDAL TRIFLUOROBUTENE | NIPPON BAYER AGROCHEM CO LTD | 2001-01-23 | — | — | JP | disclosed |
| WO-2001002378-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (DE) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352335-B2 | Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)THIO]-thiazole | THOC2, CTPS2, SULT1E1 | KDM4E 1882/4885POLB 2394/4885LMNA 3619/4885 |
| US-11634397-B2 | Process and intermediates for the preparation of Fluensulfone | SULT2A1, SULT1E1, SULT1A1 | KDM4E 2960/4885POLB 1832/4885LMNA 3887/4885 |
| US-11026425-B2 | Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | DDT, ACHE, AADAC | KDM4E 2951/4885POLB 4639/4885LMNA 3855/4885 |
| US-20070155706-A1 | Active substance combinations that have nemticidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | ACHE, AADAC, DDT | KDM4E 2856/4885POLB 4259/4885LMNA 2255/4885 |
| US-20210070719-A1 | SYNTHESIS OF 5-CHLORO-2-[(3,4,4-TRIFLUORO-3-BUTEN-1-YL)THIO]-THIAZOLE | THOC2, CTPS2, SULT1E1 | KDM4E 1882/4885POLB 2394/4885LMNA 3619/4885 |
| US-20220002258-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE | SULT2A1, SULT1E1, SULT1A1 | KDM4E 2960/4885POLB 1832/4885LMNA 3887/4885 |
| US-20210387955-A1 | SYNTHESIS OF 1,1,2-TRIFLUORO-4-(SUBSTITUTED SUFONYL)-BUT-1-ENE | SULT1E1, CYP2F1, CYP1B1 | KDM4E 672/4885POLB 791/4885LMNA 1580/4885 |
| US-20060004196-A1 | Method for producing heterocyclic fluoroalkenyl sulfones | TST, MPST, STS | KDM4E 3053/4885POLB 3363/4885LMNA 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.