Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032190 | 0.86 | PPARA (0.43) | PPARAPPARGKAT8LCKBACE1 | |
| SCHEMBL22032150 | 0.83 | ALDH1A1 (0.41) | PPARAPPARGBACE1ALDH1A1HPGD | |
| SCHEMBL15344555 | 0.83 | PPARA (0.53) | PPARAPPARGKAT8LCKBACE1 | |
| SCHEMBL8389875 | 0.83 | LCK (0.47) | PPARAPPARGKAT8LCKALDH1A1 | |
| SCHEMBL3385017 | 0.81 | ALDH1A1 (0.52) | PPARAPPARGKAT8GABRPGABRD | |
| SCHEMBL11250473 | 0.80 | PPARA (0.62) | PPARAPPARGKAT8GABRPGABRD | |
| SCHEMBL13825900 | 0.80 | FFAR1 (0.47) | PPARAPPARGKAT8LCKALDH1A1 | |
| SCHEMBL5734761 | 0.80 | BACE1 (0.62) | PPARAPPARGKAT8LCKBACE1 | |
| SCHEMBL11055698 | 0.79 | ALDH1A1 (0.50) | PPARAPPARGGABRPGABRDGABRA1 | |
| SCHEMBL27888037 | 0.79 | ALDH1A1 (0.50) | PPARAPPARGGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064428-A1 | FURANO- AND THIENOPYRIMIDINES AS NEUROKINASE INHIBITORS | H. LUNDBECK A/S (DK) | 2003-08-07 | — | — | WO | disclosed |