SCHEMBL3385017

SCHEMBL3385017

CCc1ccc(C(=O)O)c(CC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 2/20 0.48
USP2 O75604 2/20 0.48
KMT2A Q03164 2/20 0.48
TSHR P16473 2/20 0.48
HPGD P15428 1/20 0.48
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
METAP2 P50579 2/20 0.46
GABRP O00591 2/20 0.46
GABRD O14764 2/20 0.46
GABRA1 P14867 2/20 0.46
GABRB1 P18505 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRA2 P47869 2/20 0.46
GABRB2 P47870 2/20 0.46
GABRA4 P48169 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11055698 0.98 ALDH1A1 (0.50) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL27888037 0.98 ALDH1A1 (0.50) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL27904900 0.98 ALDH1A1 (0.50) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL15344634 0.89 PPARA (0.47) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL1953516 0.88 CA12 (0.45) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL15344555 0.86 PPARA (0.53) ALDH1A1METAP2GABRPGABRDGABRA1
SCHEMBL200520 0.86 CYP4F2 (0.44) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL20267768 0.86 GABRP (0.46) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL15344587 0.86 PPARA (0.53) ALDH1A1MEN1USP2KMT2ATSHR
SCHEMBL1287171 0.85 ALDH1A1 (0.54) ALDH1A1MEN1USP2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
EP-3230339-B1 EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL TORAY INDUSTRIES (JP) 2022-03-23 EP disclosed
US-20170362376-A1 EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-12-21 US disclosed
EP-3230339-A1 EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL Toray Industries, Inc. (JP) 2017-10-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
WO-2016087935-A1 EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-09 WO disclosed
US-9068074-B2 Composition for formation of cured epoxy resin, and cured products thereof NIPPON SODA CO., LTD. (JP) 2015-06-30 US disclosed
US-20150031668-A1 CHROMAN DERIVATIVES AS TRPM8 INHIBITORS AMGEN INC (US) 2015-01-29 US disclosed
US-8653160-B2 Inclusion complex containing epoxy resin composition for semiconductor encapsulation NIPPON SODA CO., LTD. (JP) 2014-02-18 US disclosed
CN-101679244-B 5-membered heterocyclic derivative and use thereof for medical purposes KISSEI PHARMACEUTICAL 2014-01-01 CN disclosed
EP-0919870-A1 Photosensitive resin composition and photosensitive element using the resin composition Nichigo-Morton Co Ltd (JP) 1999-06-02 EP disclosed
EP-0673916-B1 Preparation of 2,2,4-trimethyl-1,3-pentanediol dibenzoate and di(alkyl-substituted) benzoates VELSICOL CHEMICAL CORP (US) 1998-01-07 EP disclosed
EP-0416822-B1 Stain-resistant plasticizer compositions and method of making same VELSICOL CHEMICAL CORP (US) 1996-03-13 EP disclosed
EP-0673916-A1 Preparation of 2,2,4-trimethyl-1,3-pentanediol dibenzoate and di(alkyl-substituted) benzoates VELSICOL CHEMICAL CORPORATION (US) 1995-09-27 EP disclosed
US-5153342-A Esterification of 2,2,4-trimethyl-1,3-pentanediol with (alkyl) benzoic acids using basic catalysts HULS AMERICA INC. (US) 1992-10-06 US disclosed
US-5134208-A Polymerization process SHELL OIL COMPANY (US) 1992-07-28 US disclosed
US-5039728-A Floor and wall coverings; vinly chloride homo- and copolymers HULS AMERICA INC. (US) 1991-08-13 US disclosed
US-5006585-A Hydroxy ester compounds, stain resistance, vinyl chloride polymers HULS AMERICA INC. (US) 1991-04-09 US disclosed
EP-0416822-A2 Stain-resistant plasticizer compositions and method of making same VELSICOL CHEMICAL CORPORATION (US) 1991-03-13 EP disclosed
US-3976636-A Process and compounds THE UPJOHN COMPANY (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031668-A1 CHROMAN DERIVATIVES AS TRPM8 INHIBITORS TRPM8, TRPM5, TRPM7 ALDH1A1 4469/4885MEN1 243/4885USP2 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.