Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 4/20 | 0.48 |
| ▸ | FNTB | P49356 | 4/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471987 | 0.86 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL31472005 | 0.86 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7168316 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| Bromide SCHEMBL6415674 | 0.84 | CYP11B1 (0.46) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| SCHEMBL6366103 | 0.83 | CYP11B1 (0.79) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6846552 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| Bromide SCHEMBL3625451 | 0.82 | CYP11B1 (0.77) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL16892166 | 0.81 | CYP11B1 (0.60) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Bromide SCHEMBL8303322 | 0.79 | CYP11B1 (0.72) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6776094 | 0.78 | CYP11B1 (0.62) | CYP11B1CYP11B2ALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |