Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629168 | 0.98 | LMNA (0.60) | LMNATHRBALDH1A1MAPK1TDP1 | |
| Butane SCHEMBL1088110 | 0.93 | LMNA (0.55) | LMNATHRBALDH1A1 | |
| Acetonitrile SCHEMBL7254198 | 0.87 | LMNA (0.48) | LMNA | |
| Alcohol SCHEMBL1490179 | 0.84 | LMNA (0.80) | LMNATHRBALDH1A1TDP1 | |
| Formic Acid SCHEMBL6366884 | 0.82 | LMNA (0.67) | LMNATHRB | |
| Propionaldehyde SCHEMBL1523503 | 0.82 | LMNA (0.67) | LMNATHRBALDH1A1MAPK1TDP1 | |
| SCHEMBL10762210 | 0.82 | LMNA (0.52) | LMNATHRBALDH1A1 | |
| Propylene Glycol SCHEMBL9621813 | 0.80 | LMNA (0.50) | LMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL11485155 | 0.80 | LMNA (0.63) | LMNATHRBALDH1A1MAPK1TDP1 | |
| Malonaldehyde SCHEMBL6704192 | 0.80 | LMNA (0.63) | LMNATHRBALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006442-A1 | NOVEL PREPARATION PROCESS OF 1,3-OXAZOLE-2-THIOL | BAYER CROPSCIENCE AG (DE) | 2003-01-23 | — | — | WO | disclosed |