Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL726007

N.N.NCCN1CCOCC1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
ALOX15 P16050 1/20 0.60
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.45
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
DUSP3 P51452 1/20 0.41
GAA P10253 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
POLB P06746 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.38
DAO P14920 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9444 0.97
Hydrochloric Acid SCHEMBL1168021 0.95 KEAP1 (0.70) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
Hydrochloric Acid SCHEMBL8859956 0.95 KEAP1 (0.70) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
SCHEMBL1307205 0.95 KEAP1 (0.70) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
SCHEMBL27350451 0.95 KEAP1 (0.70) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
SCHEMBL10917755 0.95 KEAP1 (0.70) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
Ethylamine SCHEMBL4594605 0.90 SMN1; SMN2 (0.64) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
Ethylene Glycol SCHEMBL10850451 0.88 KDM4E (0.61) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
SCHEMBL1685458 0.88 KEAP1 (0.61) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1
SCHEMBL2244319 0.88 SMN1; SMN2 (0.61) KEAP1SMN1; SMN2ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609426-B1 FLUORESCENCE LABELING REAGENTS AND USES THEREOF TEXAS A & M UNIV SYS (US) 2018-12-19 EP disclosed
US-9896522-B2 Solid phase fluorescence labeling reagents and uses thereof THE TEXAS A&M UNIVERSITY SYSTEM (US) 2018-02-20 US disclosed
US-20130224870-A1 FLUORESCENCE LABELING REAGENTS AND USES THEREOF THE TEXAS A&M UNIVERSITY SYSTEM (US) 2013-08-29 US disclosed
EP-2609426-A2 FLOURESCENCE LABELING REAGENTS AND USES THEREOF The Texas A&M University System (US) 2013-07-03 EP disclosed
WO-2012027717-A2 FLOURESCENCE LABELING REAGENTS AND USES THEREOF THE TEXAS A&M UNIVERSITY SYSTEM (US) 2012-03-01 WO disclosed