Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264632 | 0.98 | HSD17B10 (0.40) | HSD17B10SIGMAR1SLC6A9POLBL3MBTL1 | |
| SCHEMBL7264621 | 0.87 | SIGMAR1 (0.37) | HSD17B10SIGMAR1 | |
| SCHEMBL7261202 | 0.85 | SLC6A9 (0.33) | HSD17B10SIGMAR1SLC6A9 | |
| SCHEMBL9187258 | 0.84 | SIGMAR1 (0.43) | HSD17B10SIGMAR1POLBL3MBTL1 | |
| SCHEMBL18840384 | 0.84 | HSD17B10 (0.40) | HSD17B10SIGMAR1SLC6A9FOLH1 | |
| SCHEMBL16185241 | 0.84 | HSD17B10 (0.40) | HSD17B10SIGMAR1SLC6A9FOLH1 | |
| SCHEMBL18840391 | 0.84 | HSD17B10 (0.40) | HSD17B10SIGMAR1SLC6A9FOLH1 | |
| SCHEMBL8672786 | 0.83 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL8672794 | 0.83 | HSD17B10 (0.53) | HSD17B10L3MBTL1 | |
| SCHEMBL18843661 | 0.82 | HSD17B10 (0.39) | HSD17B10SIGMAR1SLC6A9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38329-E1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO IMAGING S.P.A. (IT) | 2003-11-25 | — | — | US | claimed |
| EP-0872479-B1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO SPA (IT) | 2002-09-04 | — | — | EP | claimed |
| US-6149890-A | 12-CROWN-4-AMINE DERIVATIVE DIAGNOSTIC CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING | DIBRA S.P.A. (IT) | 2000-11-21 | — | — | US | claimed |
| EP-0872479-A1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO S.p.A. (IT) | 1998-10-21 | — | — | EP | claimed |
| US-RE38329-E1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO IMAGING S.P.A. (IT) | 2003-11-25 | — | — | US | disclosed |
| EP-0872479-B1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO SPA (IT) | 2002-09-04 | — | — | EP | disclosed |
| US-6177562-B1 | Chelated complexes of paramagnetic metals with low toxicity | DIBRA S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |
| US-6149890-A | 12-CROWN-4-AMINE DERIVATIVE DIAGNOSTIC CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING | DIBRA S.P.A. (IT) | 2000-11-21 | — | — | US | disclosed |
| EP-0872479-A1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO S.p.A. (IT) | 1998-10-21 | — | — | EP | disclosed |