SCHEMBL7260269

SCHEMBL7260269

CCCC[C](CCCN1C(=O)c2ccccc2C1=O)C(=O)OCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
ACHE P22303 1/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9503716 0.85 ALDH1A1 (0.57) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL7424373 0.82 KMT2A (0.63) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL7852944 0.79 HPGD (0.53) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL9798967 0.78 ALDH1A1 (0.58) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL15679600 0.78 ALDH1A1 (0.55) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL9798508 0.77 HDAC8 (0.59) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL7549194 0.77 HDAC8 (0.59) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL7589770 0.77 HDAC8 (0.59) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL2618100 0.77 HDAC8 (0.59) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL7547276 0.77 HDAC8 (0.59) ALDH1A1KMT2AHSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003057688-A2 OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS PFIZER JAPAN INC. (JP) 2003-07-17 WO claimed