Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760596 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTMMP2MMP3 | |
| SCHEMBL23010072 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTMMP2MMP3 | |
| SCHEMBL8888720 | 0.83 | TDP1 (0.51) | ALDH1A1NPSR1MAPTMMP2MMP9 | |
| SCHEMBL10765243 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1TSHRHTTHSD17B10 | |
| SCHEMBL5526889 | 0.82 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL22975158 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTMMP2MMP3 | |
| SCHEMBL20556174 | 0.79 | HSD17B10 (0.49) | ALDH1A1NPSR1MAPTMMP2MMP9 | |
| SCHEMBL8527564 | 0.79 | HDAC1 (0.49) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL20634118 | 0.79 | MAOB (0.51) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL14502531 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057688-A2 | OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS | PFIZER JAPAN INC. (JP) | 2003-07-17 | — | — | WO | claimed |