Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556320 | 0.92 | MMP2 (0.51) | TDP1ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL5526889 | 0.91 | ALDH1A1 (0.48) | TDP1ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL20556174 | 0.86 | HSD17B10 (0.49) | TDP1ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL10914406 | 0.86 | HDAC1 (0.47) | TDP1ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL10928482 | 0.84 | HDAC7 (0.56) | TDP1ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7260273 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL14502531 | 0.82 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTHDAC1HDAC7 | |
| SCHEMBL7370340 | 0.82 | HSD17B10 (0.51) | ALDH1A1SMN1; SMN2HDAC1HDAC7MMP2 | |
| SCHEMBL6578347 | 0.81 | TDP1 (0.51) | TDP1ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL18945033 | 0.81 | PLA2G1B (0.49) | MAPTSMN1; SMN2RAB9AHDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5601824-A | Homobidental, trifunctional linkers used in immunologically active conjugates | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5519142-A | Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-21 | — | — | US | disclosed |