SCHEMBL7260356

SCHEMBL7260356

COc1cccc(C(COS(=O)(=O)c2ccc(C)cc2)OC(C)(C)OC)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
STAT1 P42224 1/20 0.37
AOC3 Q16853 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
CYP24A1 Q07973 2/20 0.36
PKM P14618 1/20 0.36
POLB P06746 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.35
PSMB8 P28062 1/20 0.35
PSMB5 P28074 1/20 0.35
CNR1 P21554 1/20 0.35
MAOB P27338 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7260996 0.87 CA1 (0.34) TP53MAPTAOC3CYP24A1PKM
SCHEMBL5159909 0.86 ALDH1A1 (0.38) TP53MAPTPKML3MBTL1ALDH1A1
SCHEMBL5159896 0.86 ALDH1A1 (0.38) TP53MAPTPKML3MBTL1ALDH1A1
SCHEMBL5159902 0.86 ALDH1A1 (0.38) TP53MAPTPKML3MBTL1ALDH1A1
SCHEMBL7265071 0.86 FFAR1 (0.42) TP53MAPTPOLBALDH1A1BCHE
SCHEMBL5157648 0.84 AOC3 (0.41) AOC3CHRM2CHRM1CHRM3POLB
SCHEMBL7266195 0.80 UTS2R (0.37) TP53MAPTL3MBTL1ALDH1A1BCHE
SCHEMBL2537512 0.79 CHRM2 (0.52) TP53MAPTSTAT1AOC3CHRM2
SCHEMBL2323676 0.76 TP53 (0.43) TP53MAPTSTAT1CHRM2CHRM1
SCHEMBL2363585 0.76 TP53 (0.43) TP53MAPTSTAT1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642395-B1 Esterifying mandelic acid derivative; protecting hydroxyl group and reducing ester; sulfonating and epoxidizing MITSUBISHI RAYON CO., LTD. (JP) 2003-11-04 US disclosed
EP-1236714-A1 ACETALSULFONATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING STYRENE OXIDE DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2002-09-04 EP disclosed