Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318294 | 0.89 | TP53 (0.43) | TP53MAPTKCNA5STAT1CHRM2 | |
| SCHEMBL2323676 | 0.89 | TP53 (0.43) | TP53MAPTKCNA5STAT1CHRM2 | |
| SCHEMBL2537512 | 0.81 | CHRM2 (0.52) | TP53MAPTSTAT1CHRM2CHRM1 | |
| SCHEMBL4754272 | 0.77 | GAA (0.42) | PKMPOLBALDH1A1 | |
| SCHEMBL15471681 | 0.76 | TDP1 (0.37) | MAPTL3MBTL1ALDH1A1BCHEACHE | |
| SCHEMBL15474074 | 0.76 | CA12 (0.41) | — | |
| SCHEMBL2176940 | 0.76 | MAPT (0.43) | TP53MAPTKCNA5STAT1CHRM2 | |
| SCHEMBL7260356 | 0.76 | TP53 (0.41) | TP53MAPTSTAT1CHRM2CHRM1 | |
| SCHEMBL15465418 | 0.75 | AR (0.43) | MAOBBCHE | |
| SCHEMBL2177096 | 0.74 | ALDH1A1 (0.45) | TP53MAPTKCNA5STAT1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092719-A2 | PROCESS FOR THE PREPARATION OF L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-08-04 | — | — | WO | disclosed |