Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582919 | 0.85 | BAZ2B (0.52) | BAZ2BNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL7258315 | 0.84 | BAZ2B (0.46) | ALOX15BAZ2BNPC1RAB9AITGB3 | |
| SCHEMBL7254621 | 0.79 | TP53 (0.47) | TP53ALOX15MTNR1AALDH1A1L3MBTL1 | |
| SCHEMBL10630861 | 0.78 | SIGMAR1 (0.42) | HDAC1HDAC6ALDH1A1HSD17B10 | |
| SCHEMBL10630856 | 0.78 | SIGMAR1 (0.42) | HDAC1HDAC6ALDH1A1HSD17B10 | |
| SCHEMBL10681725 | 0.78 | CYP24A1 (0.55) | — | |
| SCHEMBL5582823 | 0.78 | ITGB3 (0.66) | BAZ2BNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL5582711 | 0.77 | BAZ2B (0.52) | BAZ2BNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL10341502 | 0.77 | ITGB3 (0.59) | BAZ2BNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL11741915 | 0.77 | NPC1 (0.44) | BAZ2BNPC1RAB9AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087046-A1 | NOVEL AMINOTETRALINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |