Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110650 | 0.84 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL6675589 | 0.81 | MCHR1 (0.70) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL1499569 | 0.80 | TDP1 (0.92) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL6110041 | 0.80 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL14831012 | 0.78 | ALDH1A1 (0.79) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL5583042 | 0.77 | TDP1 (0.81) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL6678254 | 0.77 | MCHR1 (0.75) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL6678768 | 0.76 | MCHR1 (1.00) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL12845484 | 0.76 | LMNA (0.72) | MCHR1TDP1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL542239 | 0.76 | TDP1 (0.74) | MCHR1TDP1ALDH1A1NFKB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087044-A2 | NOVEL CARBOXAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |