Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156353 | 0.83 | KMT2A (0.59) | NPC1RAB9AKMT2AKDM4EHSD17B10 | |
| SCHEMBL4788167 | 0.83 | NPC1 (0.56) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL23106548 | 0.82 | NOTUM (0.49) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL15377081 | 0.82 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL3032013 | 0.81 | MAPT (0.49) | NPC1RAB9AKMT2AKDM4EHSD17B10 | |
| SCHEMBL13572955 | 0.81 | TSHR (0.73) | NPC1RAB9AKDM4EHSD17B10HPGD | |
| SCHEMBL8589773 | 0.81 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL14438048 | 0.81 | KMT2A (0.62) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL8050653 | 0.81 | PTGS2 (0.52) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8235977 | 0.81 | ALDH1A1 (0.67) | NPC1RAB9AKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003016293-A1 | OXADIAZOLYL AND THIADIAZOLYL BENZOYL UREAS AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-02-27 | — | — | WO | disclosed |