Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL7260668 | 0.78 | F7 (0.65) | ALDH1A1KDM4ENPSR1 | |
| Picolamine SCHEMBL27476690 | 0.78 | NAPRT (0.59) | NAPRTKDM4ECYP3A4RECQLCYP1A2 | |
| Picolamine SCHEMBL28291842 | 0.76 | NAPRT (0.56) | NAPRTKDM4ECYP3A4RECQLCYP1A2 | |
| Picolamine SCHEMBL17850 | 0.76 | — | — | |
| Picolamine SCHEMBL29394769 | 0.76 | — | — | |
| Picolamine SCHEMBL30046657 | 0.76 | — | — | |
| Benzylamine SCHEMBL10458178 | 0.74 | LOXL2 (0.56) | ALDH1A1POLBTSHRCYP3A4CYP1A2 | |
| SCHEMBL10353332 | 0.74 | TSHR (0.67) | ALDH1A1MAPTTSHRCYP3A4RECQL | |
| SCHEMBL10352436 | 0.74 | TSHR (0.67) | ALDH1A1MAPTTSHRCYP3A4RECQL | |
| SCHEMBL7260670 | 0.74 | TSHR (0.67) | ALDH1A1MAPTTSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |