Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL7418787 | 0.85 | HTR2A (0.59) | LOXL2L3MBTL1CYP2C19ALDH1A1GAA | |
| SCHEMBL27262508 | 0.82 | NPC1 (0.60) | L3MBTL1CYP2C9ALDH1A1LMNAPLG | |
| Benzylamine SCHEMBL2841170 | 0.80 | LOXL2 (0.78) | LOXL2CYP2D6TSHRCYP1A2CYP2C9 | |
| Benzylamine SCHEMBL2841167 | 0.80 | LOXL2 (0.78) | LOXL2CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL3515654 | 0.78 | GBA1 (0.53) | L3MBTL1CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL1662783 | 0.78 | GBA1 (0.53) | L3MBTL1CYP2C9CYP2C19ALDH1A1GAA | |
| Benzylamine SCHEMBL25352130 | 0.78 | LOXL2 (0.74) | LOXL2CYP2D6TSHRCYP1A2CYP2C9 | |
| Benzylamine SCHEMBL3188490 | 0.78 | LOXL2 (0.74) | LOXL2L3MBTL1CYP2D6TSHRCYP1A2 | |
| Benzylamine SCHEMBL6429492 | 0.78 | LOXL2 (0.74) | LOXL2CYP2D6TSHRCYP1A2CYP2C9 | |
| Benzylamine SCHEMBL8464909 | 0.78 | LOXL2 (0.74) | LOXL2CYP2D6TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4911750-A | Mixture of a 1,2,4-triazole and phosphorus compound | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4452625-A | 1,2,4-TETRAZOLE COMPOUND WITH A CYCLOPROPANE CARBOXY COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-05 | — | — | US | disclosed |