Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | APEX1 | P27695 | 3/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | DRD1 | P21728 | 2/20 | 0.68 |
| ▸ | DRD4 | P21917 | 2/20 | 0.68 |
| ▸ | DRD5 | P21918 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 2/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL29018882 | 0.98 | KDM4E (0.69) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL29142228 | 0.95 | KDM4E (0.62) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL819109 | 0.90 | KDM4E (0.68) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL11668670 | 0.90 | KDM4E (0.78) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL28320413 | 0.89 | KDM4E (0.66) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL3290199 | 0.88 | KDM4E (0.81) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL29245423 | 0.86 | KDM4E (0.78) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL3289315 | 0.86 | KDM4E (0.78) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL28657094 | 0.86 | KDM4E (0.78) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL28470588 | 0.86 | MAPK1 (0.62) | KDM4EMAPTTDP1HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119931477-A | Efficient flame-retardant self-repairing coating and preparation method thereof | 苏州博源建筑装饰工程有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119220061-A | Degradable material for dining and drinking and preparation method thereof | 陈丽春 | 2024-12-31 | — | — | CN | claimed |
| CN-118903204-A | Exosome-dopamine conjugate compound, gel patch containing compound, and preparation method and application thereof | 四川大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118490714-A | Zwitterionic spreadable dressing and preparation method and application thereof | 浙江大学 | 2024-08-16 | — | — | CN | claimed |
| CN-114591193-B | Salt-resistant dopamine methacrylate amphiphilic monomer, preparation method and application | 中国石油化工股份有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-114106361-B | Polypropylene material loaded with zwitterionic polymer coating and preparation method thereof | 苏州至善新材料科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-114591468-B | Oil-water interface activation drag reducer for thickened oil cold recovery and preparation method | 中国石油化工股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116982169-A | High elastic polymer for lithium metal protection, lithium secondary battery and manufacturing method thereof | 环球石墨烯集团公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116808309-A | Collagen chitosan composite scaffold and preparation method and application thereof | 华南理工大学 | 2023-09-29 | — | — | CN | claimed |
| CN-116589758-A | Photopolymerized chitosan hydrogel and preparation and application thereof | 广东药科大学 | 2023-08-15 | — | — | CN | claimed |
| CN-110655817-B | Long-acting antibacterial multifunctional coating with enhanced stability and preparation and application thereof | 四川大学 | 2022-04-26 | — | — | CN | claimed |
| CN-114106361-A | Polypropylene material loaded with zwitterionic polymer coating and preparation method thereof | 苏州至善新材料科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114085413-A | Poly (N-isopropylacrylamide) -grafted polypropylene carrier material, method for the production thereof and use thereof | 苏州至善新材料科技有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-113101412-A | Long-acting stable anticoagulation biological valve material and preparation method thereof | 四川大学华西医院 | 2021-07-13 | — | — | CN | claimed |
| CN-109438716-B | Stable zwitterion surface modified nano-silver and preparation method and application thereof | 成都博岩科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-110655817-A | Long-acting antibacterial multifunctional coating with enhanced stability and preparation and application thereof | 四川大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107118305-A | A kind of preparation method of anti-adhesion medical polypropylene tissue patching material | 东南大学 | 2017-09-01 | — | — | CN | claimed |
| CN-106691874-A | Light-cured adhesive resin used for dental restoration, and preparation method thereof | 北京化工大学 | 2017-05-24 | — | — | CN | claimed |
| US-20170123229-A1 | METHOD FOR MAKING A COLORANT FILM, COLORANT FILM, AND OPHTHALMIC LENS | HON HAI PRECISION INDUSTRY CO., LTD. (TW) | 2017-05-04 | — | — | US | claimed |
| US-20130183481-A1 | MICRO-FIBER ARRAYS WITH TIP COATING AND TRANSFER METHOD FOR PREPARING SAME | CARNEGIE MELLON UNIVERSITY, CENTER FOR TECHNOLOGY TRANSFER AND ENTERPRISE CREATION (US) | 2013-07-18 | — | — | US | claimed |