SCHEMBL7260786

SCHEMBL7260786

c1coc(-c2c[nH]cc2-c2ccco2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.52
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
KDM4E B2RXH2 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
HPGD P15428 3/20 0.52
MAPT P10636 3/20 0.52
PKM P14618 2/20 0.52
ALOX15 P16050 2/20 0.52
CASP1 P29466 2/20 0.52
PTPN7 P35236 2/20 0.52
RECQL P46063 2/20 0.52
BLM P54132 2/20 0.52
CASP7 P55210 2/20 0.52
HSD17B10 Q99714 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
THRB P10828 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10504532 0.80 ADORA2A (0.42) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL1799678 0.74 ALDH1A1 (0.63) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL7266912 0.72 ALDH1A1 (0.48) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL26259380 0.72 KDM4E (0.48) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL26259566 0.72 POLB (0.48) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL1996903 0.70 PDE10A (0.43) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL7364092 0.70 PDPK1 (0.47) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL10597287 0.70 ALDH1A1 (0.46) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL7101479 0.70 TAAR1 (0.47) POLBALDH1A1MEN1KMT2AKDM4E
SCHEMBL11398828 0.70 ALDH1A1 (0.41) POLBALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066748-A Silicon containing polypyrrole THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1991-11-19 US claimed
US-4818646-A DOPING WITH TRANSITION METAL COMPLEX RICOH COMPANY, LTD. (JP) 1989-04-04 US claimed
US-20030077515-A1 Mixture of carbon nanostructure and electroconductive polymer CHEN GEORGE ZHENG (GB) 2003-04-24 US disclosed
US-5066748-A Silicon containing polypyrrole THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1991-11-19 US disclosed
US-4818646-A DOPING WITH TRANSITION METAL COMPLEX RICOH COMPANY, LTD. (JP) 1989-04-04 US disclosed
EP-0140322-B1 POLYMER CATALYST TRANSDUCERS AND USE THEREOF IN TEST KITS FOR ANALYTICAL METHODS MILES INC. (US) 1989-01-25 EP disclosed
US-4560534-A Polymer catalyst transducers MILES LABORATORIES, INC. (US) 1985-12-24 US disclosed
EP-0140322-A2 Polymer catalyst transducers and use thereof in test kits for analytical methods MILES INC. (US) 1985-05-08 EP disclosed