Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992085 | 0.88 | TSHR (0.54) | TSHRFABP4MAPK1GAAPOLB | |
| SCHEMBL11497995 | 0.86 | LMNA (0.48) | TSHRFABP4MAPK1GAAALDH1A1 | |
| SCHEMBL805216 | 0.80 | POLB (0.51) | TSHRPOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12800015 | 0.80 | POLB (0.51) | TSHRPOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11368920 | 0.79 | MAPT (0.57) | TSHRPOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12041039 | 0.79 | MAPT (0.58) | MAPK1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL19169291 | 0.78 | CA1 (0.54) | MAPK1GAAKDM4EALDH1A1LMNA | |
| SCHEMBL7000380 | 0.78 | ALDH1A1 (0.59) | MAPK1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL28887863 | 0.76 | LCK (0.49) | TSHRPOLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26106266 | 0.76 | MEN1 (0.57) | POLBKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975434-A | Processes of producing 2,5-disubstituted benzamides | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-08-17 | — | — | US | claimed |
| WO-2003055857-A1 | A PROCESS FOR SYNTHESIS OF HETEROCYCLIC AMINOALKYL BENZAMIDES | FARMACEUTSKO-HEMIJSKA INDUSTRIJA 'ZDRAVLJE' (YU) | 2003-07-10 | — | — | WO | disclosed |
| US-3975434-A | Processes of producing 2,5-disubstituted benzamides | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-08-17 | — | — | US | disclosed |