Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003260 | 0.80 | MAPT (0.57) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL27961005 | 0.79 | MAPT (0.55) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL10399533 | 0.77 | MAPT (0.53) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL5309284 | 0.77 | MAPT (0.47) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL10884047 | 0.75 | MEN1 (0.53) | MAPTKMT2AALDH1A1L3MBTL1RAB9A | |
| SCHEMBL5306728 | 0.72 | MAPT (0.57) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL8756313 | 0.71 | MAPT (0.55) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL11357255 | 0.71 | MAPT (0.57) | MAPTKMT2AALDH1A1L3MBTL1RAB9A | |
| SCHEMBL27883703 | 0.70 | MAPT (0.50) | MAPTKMT2AALDH1A1L3MBTL1APAF1 | |
| SCHEMBL9131211 | 0.70 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1L3MBTL1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045863-B1 | DETOXICATION OF ACTIVE PHARMACEUTICAL SUBSTANCES USING CYCLODEXTRINE OLIGOMERS | CERAMOPTEC INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-6642214-B1 | Oligomer consisting of two cyclodextrin molecules joined by bifunctional spacer, optionally having affinity group which interacts with molecular target structure; physical inclusion complex formed with drug reduces side effects | CERAMOPTEC INDUSTRIES, INC. | 2003-11-04 | — | — | US | disclosed |