SCHEMBL10399533

SCHEMBL10399533

O=C(O)c1c(C(=O)O)c(C(=O)O)c2c(c1C(=O)O)C(=O)c1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
ALDH1A1 P00352 5/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 2/20 0.53
KMT2A Q03164 6/20 0.53
APAF1 O14727 1/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 1/20 0.53
IDO1 P14902 1/20 0.50
MEN1 O00255 5/20 0.48
MAOA P21397 2/20 0.48
MAPK1 P28482 3/20 0.47
THRB P10828 2/20 0.47
POLB P06746 1/20 0.47
RECQL P46063 1/20 0.47
TTR P02766 5/20 0.46
KDM4E B2RXH2 3/20 0.46
USP2 O75604 2/20 0.46
PKM P14618 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003260 0.96 MAPT (0.57) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL27961005 0.94 MAPT (0.55) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL6538411 0.89 CA12 (0.44) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL27883703 0.84 MAPT (0.50) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL8756313 0.81 MAPT (0.55) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL9131211 0.80 ALDH1A1 (0.52) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL28019688 0.79 MAPT (0.55) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL6157627 0.78 MAPT (0.62) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL7260898 0.77 MAPT (0.44) MAPTALDH1A1L3MBTL1LMNAKMT2A
SCHEMBL29433161 0.77 HNF4A (0.47) MAPTALDH1A1L3MBTL1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181180-B Method for treating 3,3',4,4' -diphenyl ether dianhydride mother liquor residue 河北海力香料股份有限公司 2022-11-22 CN disclosed
CN-114181180-A Method for treating 3,3 ', 4, 4' -diphenyl ether dianhydride mother liquor residue 河北海力香料股份有限公司 2022-03-15 CN disclosed
US-4914181-A AUTOPHOTOCROSSLINKABLE; BASED ON CARBONYL-CONTAINING TETRACARBOXYLIC ACIDS AND ACYCLIC OR CARBO DIAMINES; PROTECTIVE COATINGS; PHOTORESISTS; VARNISHES; LACQUERS SEMICONDUCTORS CIBA-GEIGY CORPORATION (US) 1990-04-03 US disclosed
US-4914182-A AUTOPHOTOCROSSLINKABLE; PROTECTIVE FILMS, PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1990-04-03 US disclosed
US-4898806-A IRBADIATING AND HEATING POLYAMIC ACIDS TO POLYIMIDES CIBA-GEIGY CORPORATION (US) 1990-02-06 US disclosed
US-4808732-A CHEMICAL INTERMEDIATES FOR HOMO AND COPOLYIMIDES CIBA-GEIGY CORPORATION (US) 1989-02-28 US disclosed
US-4698295-A AUTOMATIC PHOTOCROSSLINKING CIBA-GEIGY CORPORATION (US) 1987-10-06 US disclosed
US-4696890-A POLYIMIDES BY HEATING A PHOTOCROSSLINKED POLYAMIC ESTER CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
US-4677186-A AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4629685-A PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed