Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | ATM | Q13315 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | KCNJ11 | Q14654 | 18/20 | 0.62 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.62 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.62 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258624 | 0.91 | KDM4E (1.00) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5566472 | 0.91 | KDM4E (1.00) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7258623 | 0.87 | KDM4E (0.76) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7112409 | 0.79 | KDM4E (0.62) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4260449 | 0.77 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL29405861 | 0.77 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL7256042 | 0.76 | KCNJ11 (0.87) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7112802 | 0.74 | KCNJ11 (0.59) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10036538 | 0.74 | KDM4E (0.69) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4076480 | 0.73 | HSD17B10 (0.68) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089404-A1 | NAPHTHALENE AMIDES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2003-10-30 | — | — | WO | disclosed |