Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259976 | 0.85 | STAT3 (0.40) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7262946 | 0.85 | STAT3 (0.40) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7262924 | 0.74 | TP53 (0.37) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7257094 | 0.74 | TP53 (0.37) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7257922 | 0.72 | STAT3 (0.37) | ALDH1A1NPC1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL24561 | 0.63 | TDP1 (0.67) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL13938601 | 0.62 | NPC1 (0.68) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL1926936 | 0.61 | TDP1 (0.84) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL29206621 | 0.61 | DYRK1A (0.43) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 | |
| SCHEMBL5685506 | 0.60 | MAPK1 (0.54) | ALDH1A1TP53NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | ALDH1A1 2976/4885TP53 777/4885NPC1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.