Toluic Acid

Toluic Acid

SCHEMBL7261128

Cc1ccccc1C(=O)O.O=C(O)c1cccc(Cl)c1Cl

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.75
ALDH1A1 P00352 5/20 0.57
HPGD P15428 3/20 0.52
KDM4E B2RXH2 3/20 0.52
HSD17B10 Q99714 2/20 0.52
MYC P01106 1/20 0.51
KMT2A Q03164 5/20 0.51
CYP2C9 P11712 4/20 0.51
MEN1 O00255 4/20 0.51
CYP3A4 P08684 3/20 0.51
PTGS2 P35354 3/20 0.51
AKR1C3 P42330 3/20 0.51
TTR P02766 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
LMNA P02545 2/20 0.51
CYP1A2 P05177 2/20 0.51
HIF1A Q16665 2/20 0.51
MAPT P10636 2/20 0.51
USP2 O75604 1/20 0.51
MT-CO2 P00403 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675566 0.88 TSHR (0.72) TSHRALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6267701 0.87 ALDH1A1 (0.76) TSHRALDH1A1HPGDKDM4EHSD17B10
SCHEMBL97298 0.87 TSHR (1.00) TSHRALDH1A1HPGDKDM4EHSD17B10
SCHEMBL29904615 0.87 TSHR (1.00) TSHRALDH1A1HPGDKDM4EHSD17B10
Hydrochloric Acid SCHEMBL11032955 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10
SCHEMBL2048711 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10
Ammonia Solution, Strong SCHEMBL264005 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11800294 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10
Fluoride SCHEMBL6446007 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10
SCHEMBL8616119 0.85 TSHR (0.95) TSHRALDH1A1HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653270-B2 For bleaching/cleaning fabric PROCTER & GAMBLE COMPANY 2003-11-25 US disclosed