Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496236 | 0.86 | CYP1A2 (0.49) | ALDH1A1MAPK1CDK2MAPTGAA | |
| SCHEMBL1593232 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1CDK2MAPTMEN1 | |
| SCHEMBL1496200 | 0.80 | IDO1 (0.39) | ALDH1A1CDK2MEN1KMT2AGAA | |
| SCHEMBL7260400 | 0.79 | MAPK1 (0.44) | ALDH1A1MAPK1CDK2LMNAGSK3A | |
| SCHEMBL1496186 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL14236122 | 0.75 | IDO1 (0.42) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL1593872 | 0.74 | DYRK1A (0.41) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1593429 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1496182 | 0.73 | MAP3K20 (0.38) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL29253947 | 0.72 | GSK3A (0.48) | MAPK1CDK2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068773-A1 | PYRAZOLOPYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |