SCHEMBL7262111

SCHEMBL7262111

CCCCCCCCOC(F)(F)C(F)(F)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.49
FAAH O00519 8/20 0.41
CES1 P23141 6/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NAAA Q02083 1/20 0.41
CYP1A2 P05177 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HCAR2 Q8TDS4 1/20 0.40
EPHX1 P07099 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263038 0.92 CES2 (0.39) CES2FAAHCES1MEN1KMT2A
SCHEMBL12762097 0.88 ACLY (0.37) CES2
SCHEMBL7560983 0.82 CES2 (0.46) CES2FAAHCES1MEN1KMT2A
SCHEMBL7561382 0.82 CES2 (0.46) CES2FAAHCES1MEN1KMT2A
SCHEMBL7563633 0.82 CES2 (0.46) CES2FAAHCES1MEN1KMT2A
SCHEMBL24361250 0.81 CES2 (0.52) CES2FAAHCES1MEN1KMT2A
SCHEMBL24361251 0.81 CES2 (0.52) CES2FAAHCES1MEN1KMT2A
SCHEMBL24361090 0.81 CES2 (0.52) CES2FAAHCES1MEN1KMT2A
SCHEMBL24361246 0.81 CES2 (0.52) CES2FAAHCES1MEN1KMT2A
SCHEMBL24361249 0.81 CES2 (0.52) CES2FAAHCES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526481-B1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING & MFG (US) 1995-04-26 EP claimed
EP-0526481-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS. MINNESOTA MINING & MFG (US) 1993-02-10 EP claimed
US-5118494-A Mixture of propellant surface-active dispersing agent and powdered medicment for administration by inhalation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US claimed
WO-1991014422-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-10-03 WO claimed
EP-0965335-B1 Metered-dose aerosol formulations MINNESOTA MINING & MFG (US) 2003-09-17 EP disclosed
EP-0965335-A1 Metered-dose aerosol formulations MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-22 EP disclosed
EP-0636362-B1 The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations MINNESOTA MINING & MFG (US) 1999-12-22 EP disclosed
EP-0526481-B1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING & MFG (US) 1995-04-26 EP disclosed
EP-0636362-A2 The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-01 EP disclosed