SCHEMBL7262134

SCHEMBL7262134

O=C(O)C(F)(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563385 0.98 THRB (0.48) THRBALDH1A1
Ammonia Solution, Strong SCHEMBL29599066 0.98 THRB (0.43) THRBALDH1A1
SCHEMBL9563394 0.98 THRB (0.48) THRBALDH1A1
SCHEMBL2887903 0.93 THRB (0.41) THRBALDH1A1
SCHEMBL31512502 0.93 THRB (0.41) THRBALDH1A1
SCHEMBL30772123 0.91 ALDH1A1 (0.40) THRBALDH1A1
Ammonia Solution, Strong SCHEMBL1580151 0.91 ALDH1A1 (0.40) THRBALDH1A1
SCHEMBL10635788 0.91 ALDH1A1 (0.40) THRBALDH1A1
Fluoride SCHEMBL9615437 0.91 ALDH1A1 (0.40) THRBALDH1A1
Hydrochloric Acid SCHEMBL10522740 0.91 ALDH1A1 (0.40) THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526481-B1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING & MFG (US) 1995-04-26 EP claimed
EP-0526481-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS. MINNESOTA MINING & MFG (US) 1993-02-10 EP claimed
US-5118494-A Mixture of propellant surface-active dispersing agent and powdered medicment for administration by inhalation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US claimed
WO-1991014422-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-10-03 WO claimed
EP-3546517-B1 AQUEOUS POLYTETRAFLUOROETHYLENE DISPERSION AGC INC (JP) 2023-03-08 EP disclosed
EP-3617268-B1 AQUEOUS POLYTETRAFLUOROETHYLENE DISPERSION AGC INC (JP) 2022-01-26 EP disclosed
EP-0965335-B1 Metered-dose aerosol formulations MINNESOTA MINING & MFG (US) 2003-09-17 EP disclosed
EP-0965335-A1 Metered-dose aerosol formulations MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-22 EP disclosed
EP-0636362-B1 The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations MINNESOTA MINING & MFG (US) 1999-12-22 EP disclosed
EP-0526481-B1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING & MFG (US) 1995-04-26 EP disclosed
EP-0636362-A2 The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-01 EP disclosed
EP-0331367-B1 Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU (JP) 1993-12-08 EP disclosed
EP-0526481-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS. MINNESOTA MINING & MFG (US) 1993-02-10 EP disclosed
WO-1991014422-A1 THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-10-03 WO disclosed
US-5051527-A Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU K.K. (JP) 1991-09-24 US disclosed
EP-0331367-A2 Liquid crystal compounds having fluoroalkyl radical Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-06 EP disclosed