Urea

Urea

SCHEMBL7262146

C=Cc1ccc(C=C)cc1.NC(N)=O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 2/20 0.48
TAS1R3 Q7RTX0 2/20 0.40
TAS1R1 Q7RTX1 2/20 0.40
FGFR4 P22455 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
PARP1 P09874 1/20 0.38
HDAC2 Q92769 3/20 0.38
ICAM1 P05362 1/20 0.36
SELE P16581 1/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
TRPA1 O75762 1/20 0.35
LMNA P02545 1/20 0.35
OR51E2 Q9H255 1/20 0.35
LRRK2 Q5S007 1/20 0.35
PARP10 Q53GL7 1/20 0.34
PARP3 Q9Y6F1 1/20 0.34
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL9244663 0.89 ALDH1A1 (0.58) ALDH1A1TDP1TSHRTAS1R3TAS1R1
Styrene SCHEMBL2033347 0.87 ALDH1A1 (0.70) ALDH1A1TDP1TSHRHDAC8PARP1
SCHEMBL1051273 0.85 ALDH1A1 (0.52) ALDH1A1TDP1TSHRTAS1R3TAS1R1
SCHEMBL30053335 0.83 PARP10 (0.50) ALDH1A1TDP1TSHRTAS1R3TAS1R1
Styrene SCHEMBL5164588 0.81 ALDH1A1 (0.70) ALDH1A1TDP1TSHRHDAC8PARP1
4-Vinylphenol SCHEMBL29096993 0.81 ALDH5A1 (0.48) ALDH1A1TDP1TSHRFGFR4
SCHEMBL14941432 0.81 ALDH1A1 (0.48) ALDH1A1TDP1HDAC8HDAC2HDAC3
SCHEMBL14941433 0.81 ALDH1A1 (0.48) ALDH1A1TDP1HDAC8HDAC2HDAC3
Hydrogen Peroxide SCHEMBL28624206 0.81 ALDH1A1 (0.85) ALDH1A1TDP1TSHRTAS1R3TAS1R1
SCHEMBL473081 0.80 ALDH1A1 (1.00) ALDH1A1TDP1TSHRTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653399-B2 Blend of polylactam and polydsaccharides; biodegradation DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-11-25 US disclosed
US-20020161110-A1 Water absorbent material DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-10-31 US disclosed
EP-1236507-A2 Water absorbent material comprising polysaccharide derivatives DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-09-04 EP disclosed