SCHEMBL726219

SCHEMBL726219

CCCCCCC(CCCC)Cn1nc2c(Br)c(F)c(F)c(Br)c2n1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 9/20 0.43
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28546703 0.98 CSNK2A1 (0.44) CSNK2A1LMNAMAPT
SCHEMBL28962111 0.81 CSNK2A1 (0.44) CSNK2A1MAPT
SCHEMBL18839945 0.79 LMNA (0.35) CSNK2A1LMNA
SCHEMBL9984554 0.79 LMNA (0.35) CSNK2A1LMNA
SCHEMBL726783 0.77
SCHEMBL15200733 0.75
SCHEMBL21905439 0.75
SCHEMBL726824 0.75 LMNA (0.34) LMNAMAPT
SCHEMBL29771697 0.75 CSNK2A1 (0.44) CSNK2A1MAPT
SCHEMBL30524949 0.73 LMNA (0.35) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184390-B2 Polymers with tunable band gaps for photonic and electronic applications THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2015-11-10 US disclosed
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2013-04-18 US disclosed
WO-2011156478-A2 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS GJB2, PARG, PARN CSNK2A1 4057/4885LMNA 3176/4885MAPT 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.