Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756201 | 0.93 | TSHR (0.72) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133318 | 0.92 | TSHR (0.71) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL560438 | 0.89 | TSHR (0.81) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133740 | 0.88 | TSHR (0.62) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133312 | 0.88 | TSHR (0.64) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL28242417 | 0.86 | TSHR (0.58) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL9065069 | 0.86 | TSHR (0.81) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133352 | 0.85 | TSHR (0.53) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid SCHEMBL516623 | 0.85 | TSHR (0.74) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6134355 | 0.84 | TSHR (0.59) | TSHRCYP3A4TDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024432-A2 | DEVICE FOR TRANSDERMAL ADMINISTRATION FOR THE TREATMENT OF URINARY TRACT DISORDERS | SCHWARZ PHARMA AG (DE) | 2003-03-27 | — | — | WO | disclosed |