Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263170 | 0.93 | TSHR (0.63) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL28242417 | 0.92 | TSHR (0.58) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL9065069 | 0.92 | TSHR (0.81) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL4943355 | 0.90 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL6568874 | 0.90 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL4901912 | 0.89 | TSHR (0.74) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL11820168 | 0.88 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL5512435 | 0.88 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL11207096 | 0.88 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL29141898 | 0.87 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282566-B2 | PRESSURE-SENSITIVE ADHESIVES BASED ON SIMILAR POLYMERS | AVERY DENNISON CORP (US) | 2001-03-07 | — | — | EP | disclosed |