Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268884 | 0.83 | RAB9A (0.53) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7262732 | 0.83 | MAPT (0.53) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7271120 | 0.79 | RAB9A (0.58) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30991485 | 0.77 | MAPT (0.75) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29249527 | 0.77 | MAPT (0.75) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7264114 | 0.75 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7262766 | 0.72 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28736312 | 0.71 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29633315 | 0.71 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL355054 | 0.70 | ALDH1A1 (0.50) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |