Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 known ✓ | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL16738321 | 0.91 | TDP1 (0.43) | ALDH1A1TSHRTDP1THRBHSD17B10 | |
| SCHEMBL534089 | 0.88 | TDP1 (0.48) | ALDH1A1TSHRTDP1THRBHSD17B10 | |
| Acetic Acid SCHEMBL534937 | 0.85 | TDP1 (0.40) | ALDH1A1TDP1NOS3NOS1NOS2 | |
| SCHEMBL2995741 | 0.83 | TDP1 (0.43) | ALDH1A1TSHRTDP1THRBHSD17B10 | |
| SCHEMBL17909476 | 0.83 | TSHR (0.38) | ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL25523468 | 0.80 | TDP1 (0.42) | ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL15315315 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1THRBHSD17B10 | |
| SCHEMBL25779313 | 0.79 | TDP1 (0.48) | ALDH1A1TSHRTDP1THRBHSD17B10 | |
| Propene SCHEMBL8450916 | 0.78 | TDP1 (0.41) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL5666813 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101226245-A | Antireflection film and method for producing same | DAXON TECHNOLOGY INC (CN) | 2008-07-23 | — | — | CN | disclosed |
| US-6656660-B1 | Resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-02 | — | — | US | disclosed |
| EP-1024406-A1 | Resist composition | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 2000-08-02 | — | — | EP | disclosed |