Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790664 | 0.99 | TGFBR1 (0.38) | TGFBR1 | |
| Sulfuric Acid SCHEMBL4920025 | 0.90 | TGFBR1 (0.42) | TGFBR1 | |
| Sulfuric Acid SCHEMBL3452153 | 0.88 | TGFBR1 (0.41) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL61003 | 0.86 | TGFBR1 (0.43) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL4764541 | 0.86 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL10392074 | 0.85 | TGFBR1 (0.38) | TGFBR1 | |
| Sulfuric Acid SCHEMBL28618411 | 0.85 | TGFBR1 (0.43) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL4920381 | 0.85 | TGFBR1 (0.42) | TGFBR1 | |
| SCHEMBL33606 | 0.84 | TGFBR1 (0.44) | TGFBR1 | |
| Water SCHEMBL9092030 | 0.83 | TGFBR1 (0.43) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6554869-B2 | Polymer with anionic and cationic units, the number ratio of the total of all negative charges on the anionic monomer unit(s) to the total of all positive charges on the cationic monomer unit(s) is especially from 17:3 to 3:1. | UNILEVER HOME & PERSONAL CARE USA, A DIVISION OF CONOPCO, INC. | 2003-04-29 | — | — | US | disclosed |