Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264272 | 0.89 | ACE (0.52) | ACETSHR | |
| SCHEMBL7265471 | 0.87 | ACE (0.48) | ACEACE2LTA4H | |
| SCHEMBL10929332 | 0.87 | ACE (0.57) | ACEACE2LTA4H | |
| SCHEMBL7265475 | 0.87 | ACE (0.57) | ACEACE2LTA4H | |
| SCHEMBL10829049 | 0.86 | ACE (0.56) | ACEACE2LTA4H | |
| Ammonia Solution, Strong SCHEMBL10829250 | 0.86 | ACE (0.56) | ACEACE2LTA4H | |
| SCHEMBL7265625 | 0.86 | ACE (0.56) | ACEACE2LTA4H | |
| SCHEMBL10654686 | 0.84 | ACE (0.73) | ACEACE2TSHR | |
| SCHEMBL10654654 | 0.84 | ACE (0.73) | ACEACE2TSHR | |
| SCHEMBL10661168 | 0.83 | ACE (0.72) | ACEACE2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |