Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11115544 | 0.87 | ACE (0.43) | ACELMNA | |
| Arginine SCHEMBL7264243 | 0.87 | ACE (0.41) | ACELMNA | |
| SCHEMBL7263650 | 0.87 | ACE (0.54) | ACEACE2LTA4H | |
| SCHEMBL10929332 | 0.84 | ACE (0.57) | ACELMNAACE2LTA4H | |
| SCHEMBL7265475 | 0.84 | ACE (0.57) | ACELMNAACE2LTA4H | |
| SCHEMBL7265625 | 0.83 | ACE (0.56) | ACELMNAACE2LTA4H | |
| SCHEMBL10829049 | 0.83 | ACE (0.56) | ACELMNAACE2LTA4H | |
| Ammonia Solution, Strong SCHEMBL10829250 | 0.83 | ACE (0.56) | ACELMNAACE2LTA4H | |
| SCHEMBL7263927 | 0.82 | ACE (0.48) | ACE | |
| SCHEMBL7264225 | 0.79 | ACE (0.61) | ACELMNAACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |