SCHEMBL72637

SCHEMBL72637

O=C(O)C(=O)c1ccco1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 1.00
CES2 O00748 1/20 0.77
CES1 P23141 1/20 0.77
ERCC5 P28715 1/20 0.57
FEN1 P39748 1/20 0.57
ALDH1A1 P00352 6/20 0.54
KMT2A Q03164 5/20 0.54
POLB P06746 3/20 0.54
MEN1 O00255 3/20 0.54
RECQL P46063 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
THRB P10828 1/20 0.54
APEX1 P27695 1/20 0.54
RAB9A P51151 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 3/20 0.49
NPC1 O15118 3/20 0.48
AGTR1 P30556 2/20 0.48
HSP90AA1 P07900 1/20 0.48
PAX8 Q06710 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1373142 0.98 PTPN1 (0.95) PTPN1CES2CES1ERCC5FEN1
Water SCHEMBL27331750 0.98 PTPN1 (0.95) PTPN1CES2CES1ERCC5FEN1
SCHEMBL2155972 0.87 CES2 (1.00) PTPN1CES2CES1ERCC5FEN1
SCHEMBL15233 0.87 CES2 (1.00) PTPN1CES2CES1ERCC5FEN1
SCHEMBL11448058 0.85 CES2 (0.95) PTPN1CES2CES1ERCC5FEN1
SCHEMBL8199604 0.85 CES2 (0.95) PTPN1CES2CES1ERCC5FEN1
Ammonia Solution, Strong SCHEMBL11456969 0.85 CES2 (0.95) PTPN1CES2CES1ERCC5FEN1
SCHEMBL7820958 0.85 PTPN1 (0.72) PTPN1CES2CES1ERCC5FEN1
SCHEMBL6896422 0.83 CES2 (0.81) PTPN1CES2CES1ERCC5FEN1
SCHEMBL11426338 0.83 PTPN1 (0.70) PTPN1CES2CES1ERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119242604-B Galactose oxidase mutant and application thereof in preparation of 2-oxo-2-furyl acetic acid 山东理工大学 2025-04-25 CN claimed
CN-119242604-A Galactose oxidase mutant and application thereof in preparation of 2-oxo-2-furyl acetic acid 山东理工大学 2025-01-03 CN claimed
CN-118360351-A Preparation method of 2-furylglycosides 华南理工大学 2024-07-19 CN claimed
CN-118256463-A 5-Hydroxymethylfurfural oxidase mutant, production method and application 山东理工大学 2024-06-28 CN claimed
CN-112724107-B Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof 南京工业大学 2024-01-30 CN claimed
CN-111100085-B Preparation method of 3-aryl-2H-benzo [ beta ] [1,4] benzoxazine-2-one compound 东华理工大学 2023-07-28 CN claimed
CN-115651167-A Degradable recyclable epoxy cured material, preparation method, recycling method and application 西安交通大学 2023-01-31 CN claimed
CN-114806414-A Silicon polishing composition, preparation method and application thereof 万华化学集团电子材料有限公司 2022-07-29 CN claimed
CN-112724107-A Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof 南京工业大学 2021-04-30 CN claimed
CN-112724108-A Preparation method of alpha-oxo-2-furanacetic acid 山东金城柯瑞化学有限公司 2021-04-30 CN claimed
CN-110256379-A A kind of green method synthesizing 2- furyl glyoxalic acid 济南大学 2019-09-20 CN claimed
CN-109438453-A The method of level-one amine guiding building 6- (furans -2- base) indoles simultaneously [1,2-a] quinoxaline 桂林理工大学 2019-03-08 CN claimed
CN-108101856-A Acyl group substitutes the preparation method of pyrazine compounds 河南农业大学 2018-06-01 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
WO-2000038632-A1 METHOD FOR DYING KERATIN FIBERS USING 2-OXOCARBOXYLIC ACID DERIVATIVES IN CONJUNCTION WITH NUCLEOPHILES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
EP-0550460-B1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA INC (US) 1997-04-23 EP claimed
EP-0550460-A4 1994-01-19 EP claimed
EP-0550460-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT. MOTOROLA INC (US) 1993-07-14 EP claimed
WO-1992003252-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA, INC. (US) 1992-03-05 WO claimed
US-5045128-A Printed circuits MOTOROLA, INC. (US) 1991-09-03 US claimed