Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.95 |
| ▸ | CES1 | P23141 | 1/20 | 0.95 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155972 | 0.97 | CES2 (1.00) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL15233 | 0.97 | CES2 (1.00) | CES2CES1PTPN1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL11456969 | 0.95 | CES2 (0.95) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL11448058 | 0.95 | CES2 (0.95) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL11748675 | 0.88 | CES2 (0.82) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL6896422 | 0.87 | CES2 (0.81) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL72637 | 0.85 | PTPN1 (1.00) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL15665397 | 0.84 | CES2 (0.75) | CES2CES1PTPN1ALDH1A1KMT2A | |
| SCHEMBL11538258 | 0.83 | CES2 (0.74) | CES2CES1PTPN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1373142 | 0.83 | PTPN1 (0.95) | CES2CES1PTPN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013823-A | AS CHEMICAL INTERMEDIATES; UTROTONIC AGENTS, BRONCHODIALATORS | NEW PHARMA INTERNATIONAL CORP. (UY) | 2000-01-11 | — | — | US | disclosed |
| US-5817694-A | OXYTOCICS | NEW PHARMA INTERNATIONAL CORP. (UY) | 1998-10-06 | — | — | US | disclosed |
| EP-0574185-B1 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORP (UY) | 1997-09-03 | — | — | EP | disclosed |
| EP-0574185-A2 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORPORATION (UY) | 1993-12-15 | — | — | EP | disclosed |