Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264225 | 1.00 | ACE (0.61) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL7265475 | 0.96 | ACE (0.57) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL10929332 | 0.96 | ACE (0.57) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL10829250 | 0.95 | ACE (0.56) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL7265625 | 0.95 | ACE (0.56) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL10829049 | 0.95 | ACE (0.56) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL11033719 | 0.90 | ACE (0.60) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL10829195 | 0.89 | ACE (0.51) | ACELMNAACE2LTA4HSMN1; SMN2 | |
| SCHEMBL7263961 | 0.87 | ACE (0.48) | ACELMNAACE2 | |
| SCHEMBL10932183 | 0.87 | FKBP1A (0.56) | ACELMNAACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57058694-A | — | — | None | — | — | JP | disclosed |
| JP-58126896-A | — | — | None | — | — | JP | disclosed |
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |
| JP-S58126896-A | ALANYLPROLINE DERIVATIVE AND HYPOTENSIVE AGENT CONTAINING THE SAME | AJINOMOTO CO INC | 1983-07-28 | — | — | JP | disclosed |
| JP-S5758694-A | MONOBENZYLPHOSPHORYLALANYLPROLINE AND HYPOTENSIVE COMPRISING IT | AJINOMOTO CO INC | 1982-04-08 | — | — | JP | disclosed |
| US-4316896-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1982-02-23 | — | — | US | disclosed |
| EP-0009183-B1 | PHOSPHORYL AMINOACID DERIVATIVES AND COMPOSITION FOR TREATING HYPERTENSION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1981-10-21 | — | — | EP | disclosed |
| EP-0009183-A1 | Phosphoryl aminoacid derivatives and composition for treating hypertension containing the same | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |