Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016688 | 0.90 | SRD5A2 (0.64) | SRD5A2MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL7266114 | 0.87 | CYP4F2 (0.54) | SRD5A2MAPTRAB9AGSK3BNR4A1 | |
| SCHEMBL9151166 | 0.86 | SRD5A2 (0.59) | SRD5A2MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL20157297 | 0.86 | GSK3B (0.43) | SRD5A2MAPTRAB9AGSK3BNR4A1 | |
| SCHEMBL7265825 | 0.81 | GSK3B (0.48) | SRD5A2MAPTGSK3BNR4A1MAPK1 | |
| SCHEMBL9496067 | 0.81 | SRD5A2 (0.79) | SRD5A2MAPTRAB9ANR4A1MAPK1 | |
| SCHEMBL1744667 | 0.81 | SRD5A2 (0.57) | SRD5A2MAPTRAB9AGSK3BMAPK1 | |
| SCHEMBL21550015 | 0.78 | ALDH1A1 (0.46) | SRD5A2MAPTRAB9ACYP4F2CYP4A11 | |
| SCHEMBL7161281 | 0.78 | TSHR (0.57) | NR4A1CYP4F2CYP4A11TDP1MAPK1 | |
| SCHEMBL1595355 | 0.78 | CYP4F2 (0.49) | MAPTCYP4F2CYP4A11MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |