Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016688 | 0.95 | SRD5A2 (0.64) | SRD5A2MAPTRAB9ACHEK2HPGD | |
| SCHEMBL7264267 | 0.86 | SRD5A2 (0.55) | SRD5A2MAPTRAB9AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL9148032 | 0.82 | SRD5A2 (0.55) | SRD5A2MAPTRAB9ACHEK2HPGD | |
| SCHEMBL9496067 | 0.81 | SRD5A2 (0.79) | SRD5A2MAPTRAB9ACHEK2HPGD | |
| SCHEMBL9151949 | 0.80 | SRD5A2 (0.64) | SRD5A2MAPTRAB9ACHEK2HPGD | |
| SCHEMBL7871642 | 0.78 | SRD5A2 (0.70) | SRD5A2MAPTRAB9ACHEK2HPGD | |
| SCHEMBL21550015 | 0.78 | ALDH1A1 (0.46) | SRD5A2MAPTRAB9AHPGDPPARG | |
| SCHEMBL1744667 | 0.77 | SRD5A2 (0.57) | SRD5A2MAPTRAB9AHPGDALDH1A1 | |
| SCHEMBL8047821 | 0.77 | SRD5A2 (0.57) | SRD5A2CHEK2HPGDTSHRHTT | |
| SCHEMBL2003220 | 0.77 | SRD5A2 (0.42) | SRD5A2MAPTHPGDPPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464465-B1 | Substituted aminoalkylbiphenyl derivatives, antimycotic composition containing them, and intermediates for their preparation | HOFFMANN LA ROCHE (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5239084-A | Chmical intermeidates for fungicides, mycosis | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5177067-A | Fungicides | HOFFMANN-LAROCHE INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0464465-A1 | Substituted aminoalkylbiphenyl derivatives, antimycotic composition containing them, and intermediates for their preparation | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-08 | — | — | EP | disclosed |