SCHEMBL7264269

SCHEMBL7264269

NCC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 9/20 0.62
ACE P12821 4/20 0.53
KLK7 P49862 1/20 0.51
KLK5 Q9Y337 1/20 0.51
PREP P48147 1/20 0.50
DPP4 P27487 1/20 0.50
DPP8 Q6V1X1 1/20 0.50
DPP7 Q9UHL4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7265458 0.99 FKBP1A (0.61) FKBP1AACEKLK7KLK5PREP
SCHEMBL28824228 0.90 FKBP1A (0.52) FKBP1AACEKLK7KLK5PREP
SCHEMBL6786152 0.90 FKBP1A (0.65) FKBP1AACEKLK7KLK5PREP
SCHEMBL7969235 0.90 FKBP1A (0.65) FKBP1AACEKLK7KLK5PREP
SCHEMBL6786158 0.90 FKBP1A (0.65) FKBP1AACEKLK7KLK5PREP
SCHEMBL16508636 0.88 FKBP1A (0.63) FKBP1AACEKLK7KLK5PREP
SCHEMBL30187740 0.88 FKBP1A (0.54) FKBP1AACEPREPDPP4DPP8
Hydrochloric Acid SCHEMBL10973517 0.87 FKBP1A (0.60) FKBP1AACEKLK7KLK5PREP
SCHEMBL6786208 0.87 FKBP1A (0.62) FKBP1AACEKLK7KLK5PREP
SCHEMBL6786218 0.87 FKBP1A (0.62) FKBP1AACEKLK7KLK5PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620088-A Trimer of Asn-Gly-Pro, preparation and application thereof 首都医科大学 2024-09-10 CN claimed
CN-118620088-A Trimer of Asn-Gly-Pro, preparation and application thereof 首都医科大学 2024-09-10 CN disclosed
CN-105121447-B Vinblastine derivative and preparation method and application thereof 暨南大学 2018-02-02 CN disclosed
US-4536395-A DIPEPTIDES AJINOMOTO CO., INC. (JP) 1985-08-20 US disclosed
EP-0086660-B1 RENALLY ACTIVE TETRAPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1985-07-24 EP disclosed
US-4472381-A Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them AJINOMOTO COMPANY INCORPORATED (JP) 1984-09-18 US disclosed
EP-0086660-A2 Renally active tetrapeptides SMITHKLINE BECKMAN CORPORATION (US) 1983-08-24 EP disclosed
EP-0085488-A2 Amino acid derivatives and antihypertensive drugs containing them AJINOMOTO CO., INC. (JP) 1983-08-10 EP disclosed
US-4386075-A IMPROVING KIDNEY FUNCTION SMITHKLINE BECKMAN CORPORATION (US) 1983-05-31 US disclosed