Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | TRHR | P34981 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271844 | 0.88 | PRCP (0.53) | ACERENPRCPFKBP1ACTRB1 | |
| SCHEMBL7273358 | 0.87 | ACE (0.49) | ACERENPRCPTRHRCTRB1 | |
| SCHEMBL11585814 | 0.85 | ACE (0.49) | ACERENPRCPTRHRCTRB1 | |
| SCHEMBL7264396 | 0.84 | KDM4E (0.51) | ACERENCTRB1DPP4DPP8 | |
| SCHEMBL7271897 | 0.82 | ACE (0.53) | ACERENFKBP1ACTRB1DPP4 | |
| SCHEMBL7270539 | 0.82 | MEN1 (0.40) | SMN1; SMN2KMT2ATSHR | |
| SCHEMBL7523931 | 0.82 | ACE (0.52) | ACERENTRHRDPP4DPP8 | |
| SCHEMBL7271905 | 0.81 | ACE (0.49) | ACERENTRHRCTRB1DPP4 | |
| SCHEMBL11794997 | 0.81 | ACE (0.48) | ACERENTRHRCTRB1DPP4 | |
| SCHEMBL10756344 | 0.80 | PRCP (0.62) | PRCPFKBP1ACTRB1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |